Experts looking for improved medications always consider the link between the nerve cells in the brain and neurotransmitters like glutamate. Tinnitus can occur due to the excess glutamine present in the damaged hair cells. Treatments that work as an antioxidant for glutamine are often used to fight this ailment. Let’s have a look at the brain nerve and tinnitus connection along with the new medications out there in the market.
Neurotransmitters are responsible for communication in the nerve cells. GABA, norpinephrine, acetylcholine, aspartate and dopamine are the forms of neurotransmitters. All of these attach to the nerve cells allowing only one form of neurotransmitter at a time. Some neurotransmitter like glutamine and aspartate cause increased electrical transmission amongst nerve cells while others reduce electrical activity (GABA). It’s of prime importance that neurotransmitter have both the above components like glutamine and GABA for efficient brain functioning.
Excess glutamine leads to the depletion of mitochondria, and causes the neuron withers to die. As a matter of fact, excess glutamine is the major factor responsible for the cause of tinnitus. Let’s now have a look at the2 different ways to correct this situation. One of the methods involves activation of the GABA indicators to slow down the excess glutamine. Neurontin, Valium Xanax, and Klonopin are certain antioxidants that can be used to activate GABA indicators.
The other way is to resort to conventional medication that can reduce excess glutamine flow. Memantine is a medication used as of now to cure Alzheimer’s disease. Due to the complex nature of the ear structure from within, experts reckon that transtympanic perfusion for drug delivery. The advantage with this method is that it reaches the cochlea directly upon consumption without the possibility of any side effects.
Just like memantine, caroverine is another great medication that acts like a glutamate antagonist. AM-101 is a medication likely to be introduced in the market in the near future. This medication is undergoing clinical tests, and is not expected to hit the market soon due to its time consuming process.
Campral is another medication which has made news in the recent times. It’s a medication known to treat alcohol dependence. Although individuals may experience drowsiness with this medication, the drowsiness contributes to get good sleep amongst tinnitus patients who lack sleep due to tinnitus sound.
Ginkgo Biloba Extract is another influential glutamate antagonist responsible for the cure of tinnitus. They help to eradicate the loss caused by free radicals within the body and improve the condition.
Natural Treatments have worked very well in reducing or eliminating Tinnitus while most “doctor recommended” treatments have failed.
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